Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from DFNA5 . at AA range: 200-280
Subcellular Location
Multi-pass membrane protein .
[Gasdermin-E, N-terminal]: Cell membrane
[Gasdermin-E]: Cytoplasm, cytosol .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Human Gen
1687
Observed Band
54kD
Other Name
DFNA5
ICERE-1
ICERE1
Inversely correlated with estrogen receptor expression 1
Non-syndromic hearing impairment protein 5
Background
Hearing impairment is a heterogeneous condition with over 40 loci described. The protein encoded by this gene is expressed in fetal cochlea, however, its function is not known. Nonsyndromic hearing impairment is associated with a mutation in this gene. Th