Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human PLAGL1. AA range:311-360
Subcellular Location
Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5325
Observed Band
50kD
Other Name
LOT-1
LOT1
Lost on transformation 1
PLAGL1
Pleiomorphic adenoma-like protein 1
Tumor supressor ZAC
ZAC
Zinc finger protein PLAGL1
Background
This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causa