Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human UBE3C.
Subcellular Location
proteasome complex,intracellular,nucleus,cytoplasm,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
148581
Observed Band
125kD
Other Name
HectH2
KIAA0010
KIAA10
UBE3C
Ubiquitin-protein ligase E3C
KIAA0010
KIAA10
UBE3C
Ubiquitin-protein ligase E3C
Background
function:E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. It can target itself for ubiquitination in vitro and m
protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 IQ domain.,subunit:Interacts with 26S proteasomes. Binds CAND2.,tissue specificity:Highly expressed in skeletal muscle. Detected at mu
protein ubiquitination.,similarity:Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.,similarity:Contains 1 IQ domain.,subunit:Interacts with 26S proteasomes. Binds CAND2.,tissue specificity:Highly expressed in skeletal muscle. Detected at mu