Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human TNFSF12. AA range:41-90
Subcellular Location
Cell membrane
Single-pass membrane protein.
Single-pass type II membrane protein .
[Isoform TWE-PRIL]: Cell membrane
[Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.
Single-pass membrane protein.
Single-pass type II membrane protein .
[Isoform TWE-PRIL]: Cell membrane
[Tumor necrosis factor ligand superfamily member 12, secreted form]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
8742
Observed Band
27kD
Other Name
APO3 ligand
APO3L
DR3LG
TNF-related weak inducer of apoptosis
TNFSF12
TWEAK
Tumor necrosis factor ligand superfamily member 12
APO3L
DR3LG
TNF-related weak inducer of apoptosis
TNFSF12
TWEAK
Tumor necrosis factor ligand superfamily member 12
Background
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein is a ligand for the FN14/TWEAKR receptor. This cytokine has overlapping signaling functions with TNF, but displays a much wider tiss
such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010],
such read-through transcripts are contained in GeneID 407977, TNFSF12-TNFSF13. [provided by RefSeq, Oct 2010],