Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SUPT16H. AA range:941-990
Subcellular Location
Nucleus . Chromosome . Colocalizes with RNA polymerase II on chromatin. Recruited to actively transcribed loci.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
11198
Observed Band
119kD
Other Name
Chromatin-specific transcription elongation factor 140 kDa subunit
FACT140
FACT 140 kDa subunit
FACTP140
FACT complex subunit SPT16
FACTp140
Facilitates chromatin transcription complex subunit SPT16
SUPT16H
hSPT16
Background
Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may fa
this gene encodes the 140 kDa subunit. [provided by RefSeq, Feb 2009],