Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ZEB2. AA range:71-120
Subcellular Location
Nucleus . Chromosome .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
9839
Observed Band
157kD
Other Name
HRIHFB2411
KIAA0569
SIP1
SMADIP1
Smad-interacting protein 1
ZEB2
ZFHX1B
ZFX1B
Zinc finger E-box-binding homeobox 2
Zinc finger homeobox protein 1b
Background
The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene