Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ATP2A1. AA range:548-597
Subcellular Location
Endoplasmic reticulum membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Sarcoplasmic reticulum membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Pig
Rat
Salamander
Human Gen
487
Observed Band
100kD
Other Name
ATP2A1
Calcium-transporting ATPase sarcoplasmic reticulum type
Calcium pump 1
Endoplasmic reticulum class 1/2 Ca(2+) AT
SERCA1
SR Ca(2+)-ATPase 1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
fast twitch skeletal muscle isoform
Background
This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to