Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IHC
WB
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
ELISA 2000-20000
IHC-p 1:50-300
WB 1:500-2000
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from the Internal region of human M-RIP.
Subcellular Location
Cytoplasm, cytoskeleton . Colocalizes with F-actin.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
23164/23164
Observed Band
115kD
Other Name
KIAA0864
M-RIP
MPRIP
MRIP
Myosin phosphatase Rho-interacting protein
RHOIP3
RIP3
Rho-interacting protein 3
p116Rip
M-RIP
MPRIP
MRIP
Myosin phosphatase Rho-interacting protein
RHOIP3
RIP3
Rho-interacting protein 3
p116Rip
Background
function:Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by