Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human p47 phox. AA range:341-390
Subcellular Location
Cytoplasm, cytosol . Membrane
Cytoplasmic side .
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
653361
Observed Band
44kD
Other Name
47 kDa autosomal chronic granulomatous disease protein
47 kDa neutrophil oxidase factor
NCF-1
NCF-47K
NCF1
NOXO2
Neutrophil NADPH oxidase factor 1
Neutrophil cytosol factor 1
Nox-organizing protein 2
Nox organizer 2
SH3
SH3PXD1A
Background
The protein encoded by this gene is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase. This oxidase is a multicomponent enzyme that is activated to produce superoxide anion. Mutations in this gene have been associated with chronic granulomatous disea