Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human p130 Cas. AA range:376-425
Subcellular Location
Cell junction, focal adhesion . Cytoplasm . Cell projection, axon . Unphosphorylated form localizes in the cytoplasm (By similarity). Localizes to focal adhesion sites following integrin engagement (By similarity). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9564
Observed Band
130kD
Other Name
BCAR1
Breast cancer anti-estrogen resistance protein 1
CAS
CASS1
CRK-associated substrate
CRKAS
Cas scaffolding protein family member 1
p130cas
Breast cancer anti-estrogen resistance protein 1
CAS
CASS1
CRK-associated substrate
CRKAS
Cas scaffolding protein family member 1
p130cas
Background
BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]).[supplied by OMIM, May 2009],