Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NM23-H1. AA range:3-52
Subcellular Location
Cytoplasm . Nucleus . Cell-cycle dependent nuclear localization which can be induced by interaction with Epstein-barr viral proteins or by degradation of the SET complex by GzmA.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4830
Observed Band
23kD
Other Name
GAAD
Granzyme A-activated DNase
Metastasis inhibition factor nm23
NDK A
NDPKA
NDP kinase A
NM23
NME1
Nucleoside diphosphate kinase A
Tumor metastatic process-associated protein
nm23-H1
Granzyme A-activated DNase
Metastasis inhibition factor nm23
NDK A
NDPKA
NDP kinase A
NM23
NME1
Nucleoside diphosphate kinase A
Tumor metastatic process-associated protein
nm23-H1
Background
This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this