Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human SCN9A. AA range:651-700
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cell projection, neuron projection . In neurite terminals. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
6335
Observed Band
220kD
Other Name
NENA
Neuroendocrine sodium channel
PN1
Peripheral sodium channel 1
SCN9A
Sodium channel protein type 9 subunit alpha
Sodium channel protein type IX subunit alpha
Voltage-gated sodium channel subunit alpha Nav1.7
hNE-Na
Background
This gene encodes a voltage-gated sodium channel which plays a significant role in nociception signaling. Mutations in this gene have been associated with primary erythermalgia, channelopathy-associated insensitivity to pain, and paroxysmal extreme pain d