Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MRCKB. AA range:1641-1690
Subcellular Location
Cytoplasm . Cell membrane
Cytoplasmic side . Cell junction . Cell projection, lamellipodium . Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent (By
Peripheral membrane protein
Cytoplasmic side . Cell junction . Cell projection, lamellipodium . Displays a dispersed punctate distribution and concentrates along the cell periphery, especially at the leading edge and cell-cell junction. This concentration is PH-domain dependent (By
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9578
Observed Band
194kD
Other Name
CDC42-binding protein kinase beta
CDC42BP-beta
CDC42BPB
DMPK-like beta
KIAA1124
MRCK beta
Myotonic dystrophy kinase-related CDC42-binding kinase beta
Myotonic dystrophy protein kinase-like b
Serine/threonine-protein kinase MRCK beta
CDC42BP-beta
CDC42BPB
DMPK-like beta
KIAA1124
MRCK beta
Myotonic dystrophy kinase-related CDC42-binding kinase beta
Myotonic dystrophy protein kinase-like b
Serine/threonine-protein kinase MRCK beta
Background
This gene encodes a member of the serine/threonine protein kinase family. The encoded protein contains a Cdc42/Rac-binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dyst