Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human ML-IAP. AA range:162-211
Subcellular Location
Nucleus . Cytoplasm . Golgi apparatus . Nuclear, and in a filamentous pattern throughout the cytoplasm. Full-length livin is detected exclusively in the cytoplasm, whereas the truncated form (tLivin) is found in the peri-nuclear region with marked localiz
the accumulation of tLivin in the nucleus shows positive correlation with the increase in apoptosis.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
79444
Observed Band
21kD
Other Name
BIRC7
Baculoviral IAP repeat-containing protein 7
KIAP
KIAP
Kidney inhibitor of apoptosis protein
LIVIN
Livin
ML-IAP
MLIAP
Melanoma inhibitor of apoptosis protein
RING finger protein 50
RNF50
Background
This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with c