Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human IFIH1. AA range:976-1025
Subcellular Location
Cytoplasm . Nucleus . Mitochondrion . Upon viral RNA stimulation and ISGylation, translocates from cytosol to mitochondrion. May be found in the nucleus, during apoptosis.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
64135
Observed Band
120kD
Other Name
CADM-140 autoantigen
Clinically amyopathic dermatomyositis autoantigen 140 kDa
Helicard
Helicase with 2 CARD domains
IFIH1
Interferon-induced helicase C domain-containing protein 1
Interferon-induced with helicase C domai
MDA5
RH116
Clinically amyopathic dermatomyositis autoantigen 140 kDa
Helicard
Helicase with 2 CARD domains
IFIH1
Interferon-induced helicase C domain-containing protein 1
Interferon-induced with helicase C domai
MDA5
RH116
Background
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and m
treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-depend
treatment with either agent alone only achieves reversible differentiation. Genetic variation in this gene is associated with diabetes mellitus insulin-depend