Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IP
WB
IP
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IP 1:200-500 ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MAD2L1. AA range:91-140
Subcellular Location
Nucleus . Chromosome, centromere, kinetochore. Cytoplasm . Cytoplasm, cytoskeleton, spindle pole. Recruited by MAD1L1 to unattached kinetochores (Probable). Recruited to the nuclear pore complex by TPR during interphase. Recruited to kinetochores in late
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4085
Observed Band
25kD
Other Name
HsMAD2
MAD2
MAD2-like protein 1
MAD2L1
Mitotic arrest deficient 2-like protein 1
Mitotic spindle assembly checkpoint protein MAD2A
MAD2
MAD2-like protein 1
MAD2L1
Mitotic arrest deficient 2-like protein 1
Mitotic spindle assembly checkpoint protein MAD2A
Background
MAD2L1 is a component of the mitotic spindle assembly checkpoint that prevents the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. MAD2L1 is related to the MAD2L2 gene located on chromosome 1. A MAD2 pseudogene has b