Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HRS. AA range:301-350
Subcellular Location
Cytoplasm . Early endosome membrane
Cytoplasmic side . Endosome, multivesicular body membrane
Peripheral membrane protein
Peripheral membrane protein . Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments. .
Cytoplasmic side . Endosome, multivesicular body membrane
Peripheral membrane protein
Peripheral membrane protein . Colocalizes with UBQLN1 in ubiquitin-rich cytoplasmic aggregates that are not endocytic compartments. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9146
Observed Band
80kD
Other Name
HGS
HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate
Hrs
Protein pp110
HRS
Hepatocyte growth factor-regulated tyrosine kinase substrate
Hrs
Protein pp110
Background
The protein encoded by this gene regulates endosomal sorting and plays a critical role in the recycling and degradation of membrane receptors. The encoded protein sorts monoubiquitinated membrane proteins into the multivesicular body, targeting these prot