Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human EIF2AK1. AA range:571-620
Subcellular Location
cytoplasm,
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Human Gen
27102
Observed Band
71kD
Other Name
EIF2AK1
Eukaryotic translation initiation factor 2-alpha kinase 1
HCR
HRI
Heme-controlled repressor
Heme-regulated eukaryotic initiation factor eIF-2-alpha kinase
Heme-regulated inhibitor
Hemin-sensitive initiation factor 2
KIAA1369
Background
The protein encoded by this gene acts at the level of translation initiation to downregulate protein synthesis in response to stress. The encoded protein is a kinase that can be inactivated by hemin. Two transcript variants encoding different isoforms hav