Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HCK. AA range:381-430
Subcellular Location
Cytoplasmic vesicle, secretory vesicle. Cytoplasm, cytosol.
Lipid-anchor . Cell junction, focal adhesion . Cytoplasm, cytoskeleton . Golgi apparatus . Cytoplasmic vesicle . Lysosome . Nucleus . 20% of this isoform is associated with caveolae. Localization at the cell membrane and at caveolae requires palmitoylatio
Lipid-anchor. Cell projection, podosome membrane
Lipid-anchor. Cytoplasm, cytosol. Associated with specialized secretory lysosomes called azurophil granules. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated.
Lipid-anchor . Membrane, caveola
[Isoform 1]: Lysosome. Membrane
[Isoform 2]: Cell membrane
Lipid-anchor . Cell junction, focal adhesion . Cytoplasm, cytoskeleton . Golgi apparatus . Cytoplasmic vesicle . Lysosome . Nucleus . 20% of this isoform is associated with caveolae. Localization at the cell membrane and at caveolae requires palmitoylatio
Lipid-anchor. Cell projection, podosome membrane
Lipid-anchor. Cytoplasm, cytosol. Associated with specialized secretory lysosomes called azurophil granules. At least half of this isoform is found in the cytoplasm, some of this fraction is myristoylated.
Lipid-anchor . Membrane, caveola
[Isoform 1]: Lysosome. Membrane
[Isoform 2]: Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
3055
Other Name
HCK
Hematopoietic cell kinase
Hemopoietic cell kinase
Tyrosine-protein kinase HCK
p59-HCK/p60-HCK
p59Hck
p61Hck
Hematopoietic cell kinase
Hemopoietic cell kinase
Tyrosine-protein kinase HCK
p59-HCK/p60-HCK
p59Hck
p61Hck
Background
The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respirator