Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human EAAT3. AA range:122-171
Subcellular Location
Cell membrane
Multi-pass membrane protein . Apical cell membrane
Multi-pass membrane protein . Cell junction, synapse, synaptosome . Early endosome membrane . Late endosome membrane . Recycling endosome membrane .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
6505
Observed Band
57kD
Other Name
EAAC1
EAAT3
Excitatory amino-acid carrier 1
Excitatory amino acid transporter 3
Neuronal and epithelial glutamate transporter
SLC1A1
Sodium-dependent glutamate/aspartate transporter 3
Solute carrier family 1 member 1
Background
This gene encodes a member of the high-affinity glutamate transporters that play an essential role in transporting glutamate across plasma membranes. In brain, these transporters are crucial in terminating the postsynaptic action of the neurotransmitter g