Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cox1. AA range:550-599
Subcellular Location
Microsome membrane
Peripheral membrane protein.
Peripheral membrane protein. Endoplasmic reticulum membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
5742
Observed Band
70kD
Other Name
COX-1
COX1
Cyclooxygenase-1
PGHS-1
PGH synthase 1
PHS 1
PTGS1
Prostaglandin-endoperoxide synthase 1
Prostaglandin G/H synthase 1
Prostaglandin H2 synthase 1
Background
This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Bas