Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
WB
IF
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Cofilin. AA range:61-110
Subcellular Location
Cytoplasmic side . Cell projection, lamellipodium . Cell projection, growth cone . Cell projection, axon . Colocalizes with the actin cytoskeleton in membrane ruffles and lamellipodia. Detected at the cleavage furrow and contractile ring during cytokinesi
Cytoplasmic side . Cell projection, lamellipodium membrane
Nucleus matrix . Cytoplasm, cytoskeleton . Cell projection, ruffle membrane
Peripheral membrane protein
Peripheral membrane protein
Cytoplasmic side . Cell projection, lamellipodium membrane
Nucleus matrix . Cytoplasm, cytoskeleton . Cell projection, ruffle membrane
Peripheral membrane protein
Peripheral membrane protein
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1073/1072
Observed Band
19kD
Other Name
18 kDa phosphoprotein
CFL
CFL1
CFL2
Cofilin
Cofilin, muscle isoform
Cofilin-1
Cofilin-2
non-muscle isoform
p18
CFL
CFL1
CFL2
Cofilin
Cofilin, muscle isoform
Cofilin-1
Cofilin-2
non-muscle isoform
p18
Background
cofilin 1(CFL1) Homo sapiens The protein encoded by this gene can polymerize and depolymerize F-actin and G-actin in a pH-dependent manner. Increased phosphorylation of this protein by LIM kinase aids in Rho-induced reorganization of the actin cytoskel