Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human CFTR. AA range:711-760
Subcellular Location
Apical cell membrane
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Endoplasmic reticulum membrane
Multi-pass membrane protein . Nucleus . The channel is internalized from the cell surface into an endosomal recycling compartment, from where it is recycled to the cell membrane (PubMed:17462998, PubMed:19398555, PubMed:20008117). In the oviduct and bronc
Multi-pass membrane protein . Recycling endosome membrane
Multi-pass membrane protein . Cell membrane
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Endoplasmic reticulum membrane
Multi-pass membrane protein . Nucleus . The channel is internalized from the cell surface into an endosomal recycling compartment, from where it is recycled to the cell membrane (PubMed:17462998, PubMed:19398555, PubMed:20008117). In the oviduct and bronc
Multi-pass membrane protein . Recycling endosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
1080
Observed Band
168kD
Other Name
ABCC7
ATP-binding cassette sub-family C member 7
CFTR
CFTR
Channel conductance-controlling ATPase
Cystic fibrosis transmembrane conductance regulator
cAMP-dependent chloride channel
ATP-binding cassette sub-family C member 7
CFTR
CFTR
Channel conductance-controlling ATPase
Cystic fibrosis transmembrane conductance regulator
cAMP-dependent chloride channel
Background
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP