Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human AQP4. AA range:204-253
Subcellular Location
Cell membrane
Multi-pass membrane protein . Basolateral cell membrane
Multi-pass membrane protein . Cell projection . Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane. Detected on brain astrocyte processes and astrocyte endfeet clo
Multi-pass membrane protein . Endosome membrane . Cell membrane, sarcolemma
Multi-pass membrane protein . Basolateral cell membrane
Multi-pass membrane protein . Cell projection . Activation of the vasopressin receptor AVPR1A triggers AQP4 phosphorylation at Ser-180 and promotes its internalization from the cell membrane. Detected on brain astrocyte processes and astrocyte endfeet clo
Multi-pass membrane protein . Endosome membrane . Cell membrane, sarcolemma
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
361
Observed Band
35kD
Other Name
AQP-4
AQP4
Aquaporin-4
MIWC
Mercurial-insensitive water channel
WCH4
AQP4
Aquaporin-4
MIWC
Mercurial-insensitive water channel
WCH4
Background
This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain