Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MSK1 around the phosphorylation site of Ser376. AA range:343-392
Subcellular Location
Nucleus. Cytoplasm. Predominantly nuclear. Exported into cytoplasm in response to glucocorticoid.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
9252
Observed Band
90kD
Other Name
90 kDa ribosomal protein S6 kinase 5
MSK1
Nuclear mitogen- and stress-activated protein kinase 1
RPS6KA5
RSK-like protein kinase
RSKL
Ribosomal protein S6 kinase alpha-5
S6K-alpha-5
Background
catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Appears to be activated by multiple phosphorylations on threonine and serine residues. ERK1/2 and MAPK14/p38-alpha may play a role in this process.,function