Información del producto
PR (phospho Ser190) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Progesterone Receptor around the phosphorylation site of Ser190. AA range:161-210
Subcellular Location
Nucleus. Cytoplasm. Nucleoplasmic shuttling is both hormone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases.
[Isoform 4]: Mitochondrion outer membrane .
[Isoform A]: Nucleus. Cytoplasm. Mainly nuclear.
[Isoform 4]: Mitochondrion outer membrane .
[Isoform A]: Nucleus. Cytoplasm. Mainly nuclear.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Monkey
Human Gen
5241
Observed Band
99kD
Other Name
NR3C3
Nuclear receptor subfamily 3 group C member 3
PGR
PR
Progesterone receptor
Nuclear receptor subfamily 3 group C member 3
PGR
PR
Progesterone receptor
Background
This gene encodes a member of the steroid receptor superfamily. The encoded protein mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. This