Información del producto
Información adicional
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC, IF
Concentration
1mg/mL
Recomended Dilution
WB 1:2,000 IHC 1:200 IF 1:100-200
Type Clonality
Monoclonal
Immunogen
Synthetic Peptide
Subcellular Location
Cytoplasm
Cytoplasm. Nucleus
Cytoplasm. Nucleus
Iso type
IgG1
Tissue Source
Mouse
Reactivity
Human
Human Gen
7157
Observed Band
53kDa
Other Name
Antigen NY CO 13, Cellular tumor antigen p53, FLJ92943, LFS1, Phosphoprotein p53, TP53, TRP53, tumor protein p53, Tumor suppressor p53
Background
p53 plays a major role in the cellular response to DNA damage and other genomic aberrations. The activation of p53 can lead to either cell cycle arrest and DNA repair, or apoptosis. p53 is phosphorylated at multiple sites in vivo and by several different