Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Applications
WB, IHC
Concentration
1mg/mL
Recomended Dilution
WB 1:1,000-2,000 IHC 1:200-500
Type Clonality
Polyclonal
Immunogen
Recombinant Protein
Subcellular Location
Cytoplasm
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Human Gen
836
Observed Band
32kDa
Other Name
APOPAIN antibody, CASP 3 antibody, CPP32 antibody, Cysterine protease CPP32 antibody
Background
Caspase-3 (CPP-32, Apoptain, Yama, SCA-1) is a critical executioner of apoptosis, as it is either partially or totally responsible for the proteolytic cleavage of many key proteins such as the nuclear enzyme poly(ADP-ribose) polymerase (PARP).